Eosinophilic esophagitis – blood disorder abstract.

I was diagnosed with Eosinophilic Esophagitis ten years ago in 2009. I had an endoscopy and colonoscopy at the same time. according to the procedure report there was no physical sign like white spots or red inflammation seen on the scope just seen from the esophagus biopsy.

I had not had any symptoms that I was aware of associated with this problem ever so I didn’t give that diagnosis a second thought. What I didn’t think about then was that for many years as a late teen and young adult I had regular bouts of strep throat and then in my late teens and till my early thirties I always drank a lot of coffee and it had started to feel acidy in my throat and I took regular antacid like Tagamet. I my throat would feel a little funny and would squeeze a bit when I ate bananas that were a little unripe.

I didn’t make any of these connections until recently after I got a simple virus that went into my lungs and then my throat didn’t seem to heal at all and then I started having throat pain and reactions to almost every healthy food I was eating like blueberries, strawberries, hamburger, bean chips, coconut milk. My throat felt like it was on fire and swelling. When I looked in my throat, I could see little white spots at the back of my throat. I honestly didn’t think this was going to go away.

A few months back I wrote a blog about multiple autoimmune syndrome and explained eosinophilic esophagitis. EE or EOE is an allergic inflammatory disease and typically chronic disorder that affects from one to four of every 10,000 people in the United States. It is a recently recognized disease with increasing diagnoses, resulting in part from growing awareness of the condition. https://acaai.org/allergies/types/food-allergies/types-food-allergy/eosinophilic-esophagitis.
The American Academy of Allergy Asthma and Immunology also says that this inflammatory condition likely involves both genetic and environmental causes. It seems that since I was exposed to high levels of mold in 2017 that I’ve had different symptoms where my esophagus spasms like with the mold but also with foods like rice and then after a viral infection.

I went to see a nurse practitioner at my gastroenterologist office and she said I had to try some type of proton pump inhibitor or antacid before she would prescribe any steroid because that is the protocol. She also seemed a little insistent that I get another endoscopy which I don’t want right now as I am still nursing my daughter and don’t plan to stop for several more months which poses a big problem for me with an endoscopy and all the drugs involved in having one which I didn’t want go pass in the breastmilk.

What I ended up doing was removing most foods from diet and I was only eating veggies, chicken, pork, and onions which seemed to be a small problem too but it wasn’t as bad as the fruit so I continued to eat them. The American Academy of Asthma Allergy and Immunology says, “Dietary elimination therapy has been shown to be an effective, drug-free prescription for the treatment of EOE…dietary therapy requires in-depth nutrition assessment and management. Elimination diets are not without risk and may impact nutritional status, eating pleasure, and overall quality of live.” Boy do I feel like that is an understatement. I was so depressed on July 4th this year, 2019. I couldn’t eat anything. My throat swelled from a plain hamburger I ate.

My restricted diet helped but I was concerned about the inflammation I knew was going on and those white dots at the back of my throat. I had heard that CBD oil could help with many different health issues so I decided to try that. I took about 2 pills a day for about 4 days and then I took 6 pills on the 5th day and then overnight I was able to eat everything again without any seeming problem and it seems to have stayed that way now. I am simple blown away by the CBD miracle I experienced with this. I thought for sure I would need a steroid which I would only use after August anyway which was my absolute commitment month to continue breastfeeding until. According to research from the National Institute of Health entitled Cannabidiol as an Emergent Therapeutic Strategy for Lessening the Impact of Inflammation on Oxidative Stress says that, “CBD has been shown to modulate the function of the immune system.” https://www.drperlmutter.com/wp-content/uploads/2019/01/Cannabidiol-as-an-Emergent-Therapeutic-Strategy-for-Lessening-the-Impact-of-Inflammation-on-Oxidative-Stress.pdf.

Praise the Lord! I am so happy and grateful for this substance and that feel so much better. I cannot tell you how simply awful that EOE is. Do you have an amazing story of healing from CBD oil, please share with us all to spread the hope!

Cellular respiration is a set of metabolic reactions and processes that take place in the cells of organisms to convert biochemical energy from nutrients into adenosine triphosphate (ATP), and then release waste products.

Last year my daughter had a urine organic acid test done. That test shows many different markers for yeast, bacteria, vitamins, ketones, and mitochondria. Out of all the markers every single one was out of range except one. That means my daughter’s mitochondria situation was pretty grim. She was pretty sick at the time.
The mitochondria are the energy powerhouses of every cell of the body. They convert food and oxygen into energy called ATP. Mitochondria help detox poisons like pesticides, toxins in food, pollution in the air etc. metabolism creates a leftover substance called ash or smoke and soot which is also called oxidative stress this can injure the mitochondria. Other things that can cause oxidative stress are medications, heavy metals, chemicals, and pesticides. Oxidation in nature is like when iron rusts in the presence of oxygen and moisture. Another example is when you cut an apple and it starts to turn brown that is oxidation. If you put lemon juice and antioxidant on it, it will keep it a lighter color longer.

There are a few organs that use more energy than other parts of the body. The brain uses 22-25% of total energy made in the body per day. the liver uses 21%, muscles 22%, the heart 95 and the rest of the body 16% which include the bowel, nerves, and immune function. The cells in those organs and body parts have a higher amount of mitochondria.
The mitochondria when working their best help reduce fatigue, pain, and brain thinking problems. You actually inherit your mitochondria from your mother genetically.

Jess and I for a brief time when I was making flaxseed protein bites were eating carnitine which is an amino acid that helps get nutrients from fats into the cells. Those nutrients from fats like MCT oil from coconut oil can be used as energy for the brain and body to use instead of glucose which is the form of energy that is most used.
Other nutrients the body needs to utilize fatty acids for the production of energy are carnitine, riboflavin, niacin, and COQ10. Deficiencies of folate and other B vitamins will impair mitochondria. A few other important nutrients for the mitochondria are vitamin C, glutathione, and alpha lipoic acid all of which are important for detox and lowering oxidative stress or free radicals in the body.

So Jessica had possible high oxidative stress from heavy metals, medications that I was taking and she was getting through the breast milk, other chemicals and possibly chemicals from plastics. She was also low in B2 and B12. I had been taking what I thought was a safe amount of fiorcet for migraine headaches. I had called the infant risk hotline where they have trained knowledgeable nurses to ask questions of at https://www.infantrisk.com/ to make sure the amount of medication I was taking was safe for babies and the amount I was taking they said was safe but it did cause a glutathione deficiency and likely other deficiencies too.

The bottom line with mitochondria I think is best said from Dr. Terry Wahl’s in her book The Wahl’s Protocol, “When your mitochondria aren’t powering your body correctly, everything begins to malfunction in a negative spiraling chain reaction that eventually relates to cell aging, organ dysfunction, and chronic disease. Science increasingly shows that mitochondrial strain is at the root of most of the chronic diseases afflicting modern society.” Pg. 34

A few things I recently learned about helping to boost mitochondria function are a) a mild ketogenic diet which lowers carbs, eliminates grains basically, and intends to use fats for energy instead of glucose b) calorie restriction, intermittent fasting, intellectual stimulation, and meditation. (Mito food plan comprehensive guide)
In addition the basic diet and supplements above there are a few foods especially good for the mitochondria. I thought it was really interesting learning about these foods in my functional medicine health coaching program because I was eating most of these foods on a regular basis and even in the way they were recommended. I truly do feel the best when I am eating this way. I’ll list out these foods and just a bit about what they contain and why they are so important:

1. Almonds – have mono unsaturated fat, vitamin E, glutathione. They also contain calcium and magnesium. It is recommended to only eat about a scant handful so as not to overeat these which is so easy to do at least for me.

2. Avocado – these have fiber, folate, potassium, vitamin E and glutathione.

3. Blueberries – studies from Tufts university show that proanthocyanidins in blueberries are responsible for learning and memory but they can change cell signaling patterns and oxidative patterns in neurons. I ate a lot of these instinctively when I had to have multiple X-rays when I was pregnant, this fruit is such a powerhouse.

4. Broccoli – and the broccoli family like cabbage, cauliflower, and kale contain nutrients that help the body make glutathione the master antioxidant.

5. Coconut oil – the medium chain triglycerides in coconut oil seem to used by the brain very readily as an energy source. It doesn’t require the same mechanism of digestion which lowers energy expenditure in processing through the body. Coconut oil is also antifungal, antimicrobial, and antiviral.

6. Green tea – contains catechins are protective of the mitochondria.

7. Olive oil – polyphenols which cloudy or unfiltered olive oil may have.

8. Pomegranate – protective polyphenols.

9. Salmon – rich in omega 3’s.

10. Sea weed – high in minerals the mitochondria require to function

11. Spinach – all greens, the darker color is better because it is richer in chlorophyll, carotenoids, and anti-inflammatory compounds.

histamine action. Mechanism of action of histamine and target organs. immune responses

I am not entirely sure why a low histamine diet was recommended for my daughter Jess. The doctor said it was because of a certain marker on her DNA test. She is more sensitive to histamine. That makes sense since she has had many allergic type skin reactions and many other allergic reactions from other things like foods.
I just wanted to talk a little bit about histamines what may cause it and what you can do. Histamines are associated with allergies to pets, ragweed, or anaphylaxis shock. When histamines are generated faster than can be degraded a intolerance gets created. one common sign of histamine intolerance is nasal congestion and sneezing which Jess certainly has at times. I do eat quite a few foods that are high in histamines like vinegar, kombucha, pickles, and olives. I used to eat more tuna and hot dogs too. I also used to eat quite a bit of nut butters and tomato so we were getting a good portion of histamines.

The thing is that according to the leaky gut guys __ leaky gut, candida overgrowth, SIBO, IBS, genes, and vitamin C deficiency I think speak more to anything that might be going on with Jess. She had a pretty bad gastrointestinal candida overgrowth and vitamin C deficiency.

The only thing I am doing right now for any histamine problem for Jess is higher dose probiotic, and vitamin C daily. Quercetin and DAO enzymes could be helpful if you have a histamine problem. There is quite a bit more information at https://scdlifestyle.com/2018/05/how-to-get-relief-from-a-histamine-intolerance/ to check out if this may be a problem for you.